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Fig. 2 | BMC Cancer

Fig. 2

From: Elevated expression of HSP90 and the antitumor effect of an HSP90 inhibitor via inactivation of the Akt/mTOR pathway in undifferentiated pleomorphic sarcoma

Fig. 2

Representative H&E stain (a) and immunohistochemical staining (b–g). Positive stains for p-Akt (b), p-mTOR (c), p-S6RP (d), and p-4EBP (e) in the Akt/mTOR pathway and p-MEK1/2 (f), and p-Erk1/2 (g) in the MAPK pathway. Decreased expression of PTEN in the tumor cells and immunostaining of endothelial cells (h). Immunohistochemical staining with different intensities for HSP90 (i). Immunohistochemically nuclear and/or cytoplasmic staining was judged as positive. Bar: 100 μm

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BMC Cancer

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