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Table 4 Toxicities

From: Predicting the response of patients with advanced urothelial cancer to methotrexate, vinblastine, Adriamycin, and cisplatin (MVAC) after the failure of gemcitabine and platinum (GP)

Toxicity

All grade (%)

Grade ≥3 (%)

Hematologic

 Anemia

34 (66.7 %)

25 (49.0 %)

 Neutropenia

40 (78.4 %)

29 (56.9 %)

 Thrombocytopenia

31 (60.8 %)

20 (39.2 %)

Non-hematologic

 Mucositis

7 (13.7 %)

4 (7.8 %)

 Alopecia

44 (86.3 %)

-

 Nausea/vomiting

35 (68.6 %)

3 (5.9 %)

 Anorexia

28 (56.9 %)

2 (3.9 %)

 Diarrhea/constipation

5 (9.8 %)

-

 Fatigue

10 (19.6 %)

-

 Infection

10 (19.6 %)

8 (15.7 %)