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Table 1 KDM5C staining and clinicopathologic characteristics of 221 hepatocellular carcinoma patients

From: Lysine-specific demethylase 5C promotes hepatocellular carcinoma cell invasion through inhibition BMP7 expression

Variables

KDM5C staining

Total

P*

Low

High

Age (y)

   

0.513

  ≤ 50

61 (73 %)

22 (27 %)

83

  > 50

99 (72 %)

39 (28 %)

138

Sex

   

0.405

 Male

133 (73 %)

49 (27 %)

182

 Female

31 (79 %)

8 (21 %)

39

HBsAg

   

0.072

 Negative

46 (80 %)

11 (20 %)

57

 Positive

115 (60 %)

49 (40 %)

164

HCV

   

0.169

 Negative

139 (66 %)

72 (34 %)

211

 Positive

8 (80 %)

2 (20 %)

10

AFP

   

0.534

  ≤ 20

73 (75 %)

25 (25 %)

98

  > 20

91 (74 %)

32 (26 %)

123

γ-GT(U/L)

   

0.187

  ≤ 54

72 (67 %)

36 (33 %)

108

  > 54

81 (72 %)

32 (28 %)

113

Liver cirrhosis

   

0.566

 No

29 (69 %)

13 (31 %)

42

 Yes

122 (68 %)

57 (32 %)

179

Tumor diameter (cm)

   

0.028

  ≤ 5

133 (68 %)

62 (32 %)

195

  > 5

12 (46 %)

14 (54 %)

26

Microvascular invasion

   

<0.001

 Absence

74 (80 %)

19 (20 %)

93

 Present

53 (41 %)

75 (59 %)

128

Tumor encapsulation

   

0.096

 Complete

78 (74 %)

27 (26 %)

105

 None

77 (66 %)

39 (34 %)

116

Tumor differentiation

   

<0.001

 I + II

115 (73 %)

42 (27 %)

157

 III + IV

26 (41 %)

38 (59 %)

64

TNM stage

   

0.139

 I

121 (64 %)

68 (36 %)

189

 II + III

23 (72 %)

9 (28 %)

32

  1. HBsAg hepatitis B surface antigen, AFP α-fetoprotein, γ-GT γ-glutamyl transferase, TNM tumor-nodesmetastasis
  2. *p-value < 0.05 was considered statistically significant. p-values were calculated using the Pearson chi-square test