| All samples |  | ER/PR Positive |  | ER/PR Negative |  | ||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Na | Diff.b | 95Â % CIc | P-Valued | Na | Diff.b | 95Â % CIc | P-Valued | Na | Diff.b | 95Â % CIc | P-Valued | |
Promoter regions | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
  BRCA1 | 198 | 1.7 | (0, 4) | NS | 136 | 1 | (-1, 4) | NS | 62 | 3 | (0, 8) | 0.09 |
  CD44e | 54 | 0.5 | (0, 1) | NS | 32 | 0 | (-0.4, 1) | NS | 22 | 0 | (0,2) | NS |
  ESR1e | 54 | -1.5 | (-3, 0) | 0.099 | 32 | -1 | (-4, 1) | NS | 22 | -2 | (-4, 1) | NS |
  GSTM2 | 212 | 16.8 | (13, 21) | < 0.0001 | 146 | 10 | (6, 16) | < 0.0001 | 66 | 32 | (24, 38) | < 0.0001 |
  GSTP1 | 227 | 8.3 | (6, 12) | < 0.0001 | 159 | 9 | (6, 14) | < 0.0001 | 68 | 6 | (2, 12) | 0.016 |
  MAGEA1e | 54 | -14.5 | (-22, -9) | < 0.0001 | 32 | -22 | (-30, -14) | < 0.0001 | 22 | -4 | (-12, 3) | NS |
  MSI1e | 54 | 4.7 | (2, 8) | 0.005 | 32 | 4 | (1, 10) | 0.057 | 22 | 5 | (1, 9) | 0.01 |
  NFE2L3e | 54 | 5.6 | (-4, 16) | NS | 32 | 19 | (9, 31) | 0.001 | 22 | -15 | (-26, -4) | 0.01 |
  RASSF1A | 234 | 23.5 | (19, 28) | < 0.0001 | 160 | 26 | (21, 31) | < 0.0001 | 74 | 18 | (12, 25) | < 0.0001 |
  RUNX3 | 227 | 6.6 | (4, 9) | < 0.0001 | 156 | 9 | (6, 11) | < 0.0001 | 71 | 2 | (-1, 7) | NS |
  SIX3 | 221 | 10.9 | (9, 14) | < 0.0001 | 151 | 10 | (7, 14) | < 0.0001 | 70 | 13 | (8, 19) | < 0.0001 |
  TFF1 | 230 | -21.6 | (-26, -17) | < 0.0001 | 159 | -25 | (-30, -19) | < 0.0001 | 71 | -14 | (-23, -5) | 0.002 |
Upstream of promoter | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
  EN1 | 230 | 13.1 | (10, 17) | < 0.0001 | 158 | 12 | (8, 16) | < 0.0001 | 72 | 16 | (9, 24) | < 0.0001 |
  PAX3 | 230 | 7.3 | (5, 10) | < 0.0001 | 159 | 6 | (4, 9) | < 0.0001 | 71 | 10 | (6, 15) | < 0.0001 |
  PITX2e | 54 | 7.8 | (4, 11) | < 0.0001 | 32 | 7 | (3, 10) | < 0.0001 | 22 | 10 | (1, 16) | 0.026 |
  SGK1 | 233 | 9.8 | (8, 12) | < 0.0001 | 160 | 9 | (7, 12) | < 0.0001 | 73 | 11 | (7, 16) | < 0.0001 |
Introns | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
  APC | 221 | 12.3 | (9, 16) | < 0.0001 | 153 | 12 | (8, 16) | < 0.0001 | 68 | 15 | (9, 22) | < 0.0001 |
  EGFR | 235 | 12 | (9, 15) | < 0.0001 | 161 | 15 | (11, 18) | < 0.0001 | 74 | 6 | (2, 11) | 0.009 |
  LHX2e | 54 | 8.1 | (2, 15) | 0.017 | 32 | 8 | (3, 13) | 0.006 | 22 | 9 | (-5, 22) | NS |
  RFX1 | 235 | 19.8 | (17, 23) | < 0.0001 | 161 | 20 | (16, 23) | < 0.0001 | 74 | 21 | (16, 26) | < 0.0001 |
  SOX9 | 231 | 6.2 | (3, 9) | < 0.0001 | 158 | 6 | (3, 10) | < 0.0001 | 73 | 6 | (1, 13) | 0.031 |
DNA Repeats | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
  LINE-1 | 238 | -1.5 | (-2, -1) | < 0.0001 | 162 | -2 | (-3, -1) | < 0.0001 | 76 | -1 | (-3, 0) | 0.074 |
  Sat2 | 237 | -5.4 | (-9, -2) | 0.001 | 161 | -6 | (-10, -2) | 0.003 | 76 | -5 | (-10, 1) | 0.109 |