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Table 3 Toxicity during first cycle of induction chemotherapy according to CTCAE 4.0 (76 evaluable patients) by genotype (% per group)

From: CYP39A1 polymorphism is associated with toxicity during intensive induction chemotherapy in patients with advanced head and neck cancer

 

Genotype rs7761731

Total population (n = 76)

AA (n = 33

AT (n = 36)

TT (n = 8)

Leucopenia G3/4 (%)

62.5 %

37.1 %

12.5 %

44.7 %

Infection G3/4 (%)

28.1 %

20.0 %

25.0 %

23.1 %

Renal Toxicity > G1 (%)

3.1 %

11.4 %

12.5 %

9.2 %

Thrombopenia G3 (%)

na.

na.

na.

0 %