Table 1 Clinico-pathological association of PTEN deletion
From: Partial PTEN deletion is linked to poor prognosis in breast cancer
| Â | Â | Â | PTEN FISH | Â | |
|---|---|---|---|---|---|
| Â | Â | Analyzable (n) | normal | deletion | P value |
All cancers | Â | 1239 | 81 % | 19 % | Â |
Histology | No special type | 917 | 81 % | 19 % | - |
| Â | Lobular carcinoma | 123 | 91 % | 9 % | 0.005* |
| Â | Cribriform carcinoma | 43 | 88 % | 12 % | 0.32 |
| Â | Medullary carcinoma | 39 | 54 % | 46 % | 0.0001 |
| Â | Tubular carcinoma | 28 | 96 % | 4 % | 0.04 |
| Â | Papillary carcinoma | 17 | 65 % | 35 % | 0.11 |
| Â | Mucinous carcinoma | 29 | 97 % | 3 % | 0.03 |
| Â | Other rare typesa | 43 | 58 % | 42 % | 0.007 |
pT stage | pT1 | 411 | 87 % | 13 % | 0.005 |
| Â | pT2 | 613 | 78 % | 22 % | |
| Â | pT3 | 61 | 77 % | 23 % | |
| Â | pT4 | 146 | 79 % | 21 % | |
BRE grade | Grade 1 | 308 | 93 % | 7 % | <0.0001 |
| Â | Grade 2 | 472 | 87 % | 13 % | |
| Â | Grade 3 | 457 | 68 % | 32 % | |
Nodal stage | pN0 | 524 | 82 % | 18 % | 0.18 |
| Â | pN1 | 446 | 79 % | 21 % | |
| Â | pN2 | 64 | 72 % | 28 % | |
ER status | Negative | 296 | 57 % | 43 % | <0.0001 |
| Â | Positive | 906 | 89 % | 11 % | |
PR status | Negative | 744 | 76 % | 24 % | <0.0001 |
| Â | Positive | 408 | 89 % | 11 % | |