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Table 1 The absorbance of ECs under different culture conditions of IL-6 and/or sIL-6R

From: Higher proliferation of peritumoral endothelial cells to IL-6/sIL-6R than tumoral endothelial cells in hepatocellular carcinoma

  

Control

IL-6

sIL-6R

IL-6 + sIL-6R

TECs

24 h

0.92 ± 0.01a

0.93 ± 0.01

0.95 ± 0.01

0.94 ± 0.01

48 h

1.37 ± 0.01

1.40 ± 0.01

1.39 ± 0.01

1.50 ± 0.01*

72 h

1.56 ± 0.01

1.59 ± 0.02

1.57 ± 0.01

1.66 ± 0.01*

PECs

24 h

1.16 ± 0.01

1.15 ± 0.01

1.21 ± 0.01

1.22 ± 0.01

48 h

2.25 ± 0.02

2.28 ± 0.02

2.31 ± 0.01

2.65 ± 0.01***

72 h

2.50 ± 0.01

2.53 ± 0.01

2.51 ± 0.02

2.71 ± 0.01*

  1. acell proliferation was evaluated by CCK-8 assay and results were expressed as the absorbance of each well which was read at 490 nm with a microplate reader (Nexcelom, Lawrence, MA). Culture medium (EBM-2 medium) without cells was used as blank control. All experiments were performed in triplicate
  2. Student t test was conducted between different groups with stimulation of (IL-6 and /or sIL-6R) and control group
  3. * P < 0.05; *** P < 0.001
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BMC Cancer

ISSN: 1471-2407

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