Patterns of resource utilization and cost for postmenopausal women with hormone-receptor–positive, human epidermal growth factor receptor-2–negative advanced breast cancer in Europe

Table 6 Costs contributing to monthly direct cost for chemotherapy-based and hormone therapy-based treatment

	Average monthly costs (median monthly costs) and contribution percentages^a
	Contributor	Hormone therapy 1st line, Cohort A (n = 218)		Chemotherapy 1st line, Cohort C (n = 111)		Chemotherapy 2nd line, Cohort A (n = 218)
Drug^b	Hormone therapy	€159	35.5 %	€57	1.9 %	€23	1.0 %
	Hormone therapy	(€78)		(€0)		(€0)
	Chemotherapy	NA	NA	€1145	38.4 %	€873	37.3 %
	Chemotherapy			(€942)		(€515)
	Targeted therapy	€72	16.1 %	€897	30.1 %	€863	36.9 %
	Targeted therapy	(€0)		(€0)		(€0)
	Chemotherapy complementary treatment	NA	NA	€325	10.9 %	€135	5.8 %
	Chemotherapy complementary treatment			(€0)		(€0)
	Total	€231	51.6 %	€2424	81.2 %	€1894	81.0 %
Resource	Diagnostic/monitoring	€135	30.2 %	€298	10.0 %	€212	9.1 %
	Diagnostic/monitoring	(€114)		(€225)		(€157)
	Hospitalization^c	€12	2.6 %	€75	2.5 %	€54	2.3 %
	Hospitalization^c	(€0)		(€0)		(€0)
	Physician visits^d	€64	14.4 %	€163	5.5 %	€155	6.6 %
	Physician visits^d	(€19)		(€113)		(€109)
	Other HCP visits^e	€5	1.0 %	€15	0.5 %	€7	0.3 %
	Other HCP visits^e	(€0)		(€5)		(€3)
	Palliative care^f	€0.3	0.1 %	€10	0.3 %	€15	0.6 %
	Palliative care^f	(€0)		(€0)		(€0)
	Total	€216.3	48.4 %	€561	18.8 %	€443	19.0 %
Average monthly cost		€447		€2983		€2338

Abbreviations: HCP healthcare professional, NA not applicable
^aCosts and percentages are rounded to the nearest Euro (where possible) and 10th place, respectively, which may lead to slight differences in some totals. Note that median costs may be markedly different from the average costs. For example, if a large number of patients in a group had no hospitalizations while a small number of patients in the group had hospitalizations, the median costs may be zero even though the average costs are high
^bIncludes drug cost only to avoid double-counting; administration costs are included in the medical costs below under the assumption that all outpatient visits are recorded
^cIncludes daycare inpatient treatments (e.g., drug administration or monitoring) and longer hospitalization
^dOncology consultant office, general practitioner, ambulatory care, and nurse home visit
^ePhysiotherapist, dietician, and psychotherapist visits
^fIncludes daycare and hospitalization for palliative care

ISSN: 1471-2407