Table 3 Univariate and multivariate analysis
Univariate analysis | ||||
|---|---|---|---|---|
OS | HR | Lower 95 % CI | Upper 95 % CI | p.value |
 Gender (male or female) | 0.76 | 0.34 | 1.67 | 0.5 |
 Age (<65 or 2^ 65) | 0.98 | 0.94 | 1.03 | 0.5 |
 Performance status (0 or 1) | 1.78 | 0.42 | 7.5 | 0.43 |
 Resection of primary tumor (yes or no) | 0.7 | 0.2 | 1.6 | 0.43 |
 Ascitis (yes or no) | 1.7 | 0.7 | 4.1 | 0.22 |
 Liver metastasis (yes or no) | 1.2 | 0.59 | 2.6 | 0.55 |
 Lung metastasis (yes or no) | 0.77 | 0.34 | 1.7 | 0.51 |
 Lymph metastasis (yes or no) | 1.9 | 0.86 | 4.2 | 0.1 |
 Multiple metastasis (yes or no) | 2.5 | 1.1 | 5.9 | 0.03 |
 Peritoneal metastasis (yes or no) | 2.5 | 1.2 | 5.2 | 0.01 |
 Anti p53 antibody (positive or negative) | 0.8 | 0.3 | 1.7 | 0.61 |
 IHC of p53 protein (positive or negative) | 0.58 | 0.21 | 1.6 | 0.3 |
 KRAS (wild or mutant) | 1.29 | 0.54 | 2.75 | 0.63 |
PFS | ||||
 Gender (male or female) | 1.6 | 0.9 | 3.03 | 0.1 |
 Age (<65 or^65) | 0.99 | 0.96 | 1.02 | 0.53 |
 Performance status (0 or 1) | 1.8 | 0.23 | 2.47 | 0.64 |
 Resection of primary tumor (yes or no) | 1.5 | 0.72 | 3.1 | 0.99 |
 Ascitis (yes or no) | 0.6 | 0.28 | 1.43 | 0.29 |
 Liver metastasis (yes or no) | 0.54 | 0.28 | 1 | 0.07 |
 Lung metastasis (yes or no) | 2.8 | 1.59 | 5.2 | 4E-04 |
 Lymph metastasis (yes or no) | 0.47 | 0.26 | 0.85 | 0.01 |
 Multiple metastasis (yes or no) | 0.9 | 0.51 | 1.6 | 0.72 |
 Peritoneal metastasis (yes or no) | 0.73 | 0.37 | 1.45 | 0.27 |
 Anti p53 antibody (positive or negative) | 0.9 | 0.49 | 1.6 | 0.73 |
 IHC of p53 protein (positive or negative) | 1 | 0.51 | 1.9 | 0.99 |
 KRAS (wild or mutant) | 0.98 | 0.49 | 1.9 | 0.94 |
Multivariate analysis | ||||
OS | HR | Lower 95 % CI | Upper 95 % CI | p.value |
 Peritoneal metastasis (yes or no) | 2.3 | 1.1 | 5.1 | 0.02 |
PFS | ||||
 Lung metastasis (yes or no) | 2.46 | 1.34 | 4.51 | 0.003 |
 Lymph metastasis (yes or no) | 0.5 | 0.28 | 0.97 | 0.04 |