Fig. 3

a Changes of methylation status of the HIN-1 gene detected by methylation-specific PCR in parental ES2 cells and the derived paclitaxel-resistant ES2TR160 cells before and after 5-aza-2-dC treatment for 3 or 6 days. M represents methylation and U represents unmethylation. b Representative figure of HIN-1 mRNA expression in ES2 and ES2TR160 cells treated with or without 5-aza-2-dC for 3 or 6 days. c Bar figure of the folds of HIN-1 mRNA expression in the ES2 and ES2TR160 cells treated with or without 5-aza-2-dC for 6 days