Advertisement
Table 3 Optimal strategy according to the Ceiling Ratio in Base-case and Multivariate Scenarios
| Optimal Strategy | ||||||
|---|---|---|---|---|---|---|
| Ceiling Ratio | No Screening | Biennial G-FOBT | Annual G-FOBT | Colonoscopy every 10 years | Biennial I-FOBT | Annual I-FOBT |
| In term of LYs | ||||||
| Base-case scenario | ||||||
| [0, 19,838] | Extended Dominance | Dominance | Dominance | (19,838, 23,742] | (23,742, +∞) | |
| Non-discounted Scenario (Discount Rate = 0 %) | ||||||
| [0, 14,681] | Extended Dominance | Dominance | Dominance | (14,681, 15,856] | (15,856, +∞) | |
| In term of QALYs | ||||||
| Base-case scenario | ||||||
| [0, 2976] | Extended Dominance | Dominance | Dominance | (2976, 4087] | (4087, +∞) | |
| Non-discounted Scenario (Discount Rate = 0 %) | ||||||
| [0, 2510] | Extended Dominance | Dominance | Dominance | (2510, 3294] | (3294, +∞) | |
| Ramsey’s Utility Set Scenario (Cancer free = 1.00; S1/S2 = 0.90; S3 = 0.80; S4 = 0.76) | ||||||
| [0, 12,294] | Extended Dominance | Dominance | Dominance | (12,294, 15,279] | (15,279, +∞) | |
| Ness’s Utility Set Scenario (Cancer free = 0.91; S1 = 0.74; S2 = 0.70; S3 = 0.50; S4 = 0.25) | ||||||
| [0, 9278] | Extended Dominance | Dominance | Dominance | (9278, 11,803] | (11,803, +∞) | |
| Sharp’s Utility Set Scenario (Cancer free = 0.94; S1/S2/S3/S4 = 0.80) | ||||||
| [0, 12,505] | Extended Dominance | Dominance | Dominance | (12,505, 15,460] | (15,460, +∞) | |
