Skip to main content

Advertisement

Table 2 Cell cycle profiles; DNA content was determined by propidium iodide staining of fixed cells and flow cytometric analysis; results are displayed as % of cells (mean ± SEM) on three different donors 24 h after incubation with a 10 nM concentration of PM01215 and PM02781

From: The Aplidin analogs PM01215 and PM02781 inhibit angiogenesis in vitro and in vivo

  G1 phase S phase G2 phase
control 42.3 ± 2.5 14.9 ± 1.4 40.3 ± 1.4
PM01215 61.1 ± 1.7* 3.7 ± 1.0* 34.1 ± 2.4*
PM 02781 61.8 ± 1.0* 3.4 ± 0.8* 33.5 ± 1.7*
  1. *Indicate p values < 0.05