Fig. 2
From: Correlation between apparent diffusion coefficients and HER2 status in gastric cancers: pilot study
A 58-year-old man with gastric cancer, at stage III B (T3N3M0). Axial diffusion weighted image (b = 1000 sec/mm2) (a) shows a hyperintense lesion in antrum (arrow) of stomach with a maximum diameter of 6.0 cm. Note the bright lymph node metastasis (curved arrow). An oval region-of-interest (ROI) with an area of 22.0 mm2 is placed within the solid part of the lesion in corresponding apparent diffusion coefficient (ADC) map (b), which shows restricted mean and minimal ADC values as 0.918 and 0.867 × 10−3 mm2/s. Photomicrograph (Hematoxylin & Eosin staining, ×200) (c) reveals signet ring cell carcinoma with a Lauren classification of diffuse type. HER2 immunohistochemical assay (d) shows no membrane staining is observed (score 0)