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Table 1 Hesperidin (HES)-induced cell cycle arrest at G0/G1 phase of HeLa cells

From: Hesperidin inhibits HeLa cell proliferation through apoptosis mediated by endoplasmic reticulum stress pathways and cell cycle arrest

Concentration (μM)

The percentage of cells (%)

G0/G1

S

G2/M

0

42.10 ± 2.42

31.70 ± 1.43

26.20 ± 1.31

40

51.70 ± 2.84*

26.95 ± 1.33

21.35 ± 1.06

80

60.30 ± 3.11*

20.45 ± 1.25

19.25 ± 0.97

160

72.20 ± 3.49*

12.10 ± 0.77

15.70 ± 0.82

  1. HeLa cells were treated with HES (0, 40, 80, and 160 μM) for 48 h. The distribution of cells in the cell cycle was measured by flow cytometry; *p <0.05 versus control group (0 μM) (two-way ANOVA followed by the Tukey’s post hoc test)