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Fig. 9 | BMC Cancer

Fig. 9

From: Epigenetic-based combinatorial resveratrol and pterostilbene alters DNA damage response by affecting SIRT1 and DNMT enzyme expression, including SIRT1-dependent γ-H2AX and telomerase regulation in triple-negative breast cancer

Fig. 9

Combination treatments did not alter epigenetic enzyme expression and their activity in MCF10A control cells. Overall DNMT enzyme activity analysis, using 20 μg of nuclear extract. After 72 h, there was no significant change in the enzyme activity in comparison to DMSO control in MCF10A control cells further highlighting the effectiveness of this combination regimen. Values are representative of three independent experiments and represented as percent of control ± SE; *P <0.05, **P <0.01

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BMC Cancer

ISSN: 1471-2407

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