The effect of pre-diagnostic vitamin D supplementation on cancer survival in women: a cohort study within the UK Clinical Practice Research Datalink

Table 2 The association of vitamin D and calcium supplementation with survival from selected cancers in women

	Deaths	Cases	Person-	Basic model		Adjusted model
			Years	HR	95 % CI	HR	95 % CI
Breast cancer
3+ prescriptions	228	842	2408.5	1.01	0.79 to 1.29	1.02	0.79 to 1.32
1–2 prescriptions	86	318	974.9	1		1
Any	314	1160	3383.3	0.80	0.71 to 0.90	0.78	0.70 to 0.88
None	1789	9952	38168.7	1		1
Colorectal cancer
3+ prescriptions	191	426	929.7	0.82	0.61 to 1.10	0.81	0.59 to 1.11
1–2 prescriptions	61	130	282.1	1		1
Any	252	556	1203.8	0.91	0.79 to 1.04	0.90	0.78 to 1.04
None	1474	3566	10090.6	1		1
Lung cancer
3+ prescriptions	323	418	384.0	0.91	0.73 to 1.12	0.86	0.70 to 1.07
1–2 prescriptions	120	141	134.1	1		1
Any	443	559	518.1	1.05	0.96 to 1.16	1.06	0.96 to 1.17
None	2313	2793	2954.1	1		1
Gynaecologic cancer
3+ prescriptions	98	220	538.1	0.74	0.49 to 1.10	0.84	0.59 to 1.30
1–2 prescriptions	36	72	152.7	1		1
Any	134	292	690.9	0.87	0.72 to 1.05	0.89	0.73 to 1.07
None	1017	2687	8033.1	1		1

The basic model is adjusted for age and period; the adjusted model is further adjusted for smoking, alcohol, BMI and area-level deprivation

ISSN: 1471-2407