Fig. 5
From: Enhancement of Cetuximab-Induced Radiosensitization by JAK-1 Inhibition
The use of JAK1i (1 μM) increased the effects of cetuximab (0.5 μg/ml) in all four cell lines when cell proliferation or apoptosis was assessed. The data represent the mean and standard error of three assessments. Top. Cell proliferation was assessed 72 h after indicated treatments and normalized to vehicle-treated cells (100 %). Bottom. Apoptosis was assessed in exponentially growing cells that were collected after 72 h treatments and analyzed using Annexin V-FICT kit