|
Parameters
|
Fisher’s exact test
|
IGF1R score 2+
|
IGF1R score 3+
|
|---|
|
p-value
|
OR
|
95 % CI
|
p-value
|
OR
|
95 % CI
|
|---|
|
Histological grade
|
<0.001
| | | | | | |
|
Grade I or II
| |
-
|
1.00
|
-
|
-
|
1.00
|
-
|
|
Grade III
| |
0.007
|
3.86
|
1.49–10.99
|
<0.001
|
6.54
|
2.57–18.53
|
|
LVI
|
0.006
| | | | | | |
|
Absent
| |
-
|
1.00
|
-
|
-
|
1.00
|
-
|
|
Present
| |
0.87
|
1.08
|
0.44–2.68
|
0.01
|
3.11
|
1.32–7.62
|
|
ER expression
|
0.004
| | | | | | |
|
Positive (≥ 10 %)
| |
-
|
1.00
|
-
|
-
|
1.00
|
-
|
|
Negative (< 10 %)
| |
0.003
|
4.54
|
1.69–13.01
|
0.01
|
3.29
|
1.32–8.46
|
|
PR expression
|
0.04
| | | | | | |
|
Positive (≥ 10 %)
| |
-
|
1.00
|
-
|
-
|
1.00
|
-
|
|
Negative (< 10 %)
| |
0.07
|
2.88
|
0.93–9.47
|
0.02
|
4.10
|
1.29–14.54
|
|
Immunophenotype
|
0.03
| | | | | | |
|
Luminal
| |
-
|
1.00
|
-
|
-
|
1.00
|
-
|
|
Triple Negative
| |
0.02
|
2.86
|
1.16–7.20
|
0.02
|
2.88
|
1.20–7.04
|
- IGF1R score 0–1+ is considered as the reference for each parameter
- IGF1R Insulin-like growth factor type 1 receptor, LVI Lymphovascular Invasion, ER Estrogen Receptor, PR Progesterone Receptor, OR Odds Ratio, 95 % CI 95 % Confidence Interval
