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Table 4 Clinical features at diagnosis for low risk patients who received level Ib-sparing and -covering IMRT

From: Investigation of the feasibility of elective irradiation to neck level Ib using intensity-modulated radiotherapy for patients with nasopharyngeal carcinoma: a retrospective analysis

Variable Irradiation of level Ib, N (%) P *
(−), n = 722 (+), n = 182
Sex    
Male 536 (74.2) 122 (67.0) .051
Female 186 (25.8) 60 (33.0)
Age    
<50 years 447 (66.1) 139 (76.4) .008
50 years 245 (33.9) 43 (23.6)
T classification    
T1 157 (21.7) 36 (19.8) .208
T2 108 (15.0) 38 (20.9)
T3 332 (46.0) 83 (45.6)
T4 125 (17.3) 25 (13.7)
N classification    
N0 206 (28.5) 21 (11.5) <.001
N1 493 (68.7) 137 (75.3)
N3 20 (2.8) 24 (13.2)
Positive RLNs  
(−) 256 (35.5) 45 (24.7) .006
(+) 466 (64.5) 137 (75.3)
Positive CLNs  
(−) 479 (66.3) 60 (33.0) <.001
(+) 243 (33.7) 122 (67.0)
Positive CLNs at supraclavicular fossa  
(−) 710 (98.3) 168 (92.3) <.001
(+) 12 (1.7) 14 (7.7)  
Chemotherapy  
(−) 147 (20.4) 15 (8.2) <.001
(+) 575 (79.6) 167 (20.1)
  1. Abbreviations: IMRT, intensity-modulated radiotherapy; RLNs, retropharyngeal lymph nodes; CLNs, cervical lymph nodes; ES, extra-capsular spread
  2. * P-values were calculated using unadjusted chi-square test (or Fisher’s exact test, if indicated)