Fig. 3

Platelets significantly increase SK-OV-3 cell invasion activity. a Results are expressed as the percentage of 59 M (black bar) and SK-OV-3 (white bar) cell invasion, in the absence and presence of platelets (plts), through Matrigel® invasion chambers relative to control chambers after 16 and 24 h (n = 6). b SK-OV-3 cells overall have a higher expression level of epithelial markers and lower expression level of mesenchymal markers compared to 59 M. Results are expressed as fold change values that represent the difference in the baseline mRNA expression level of epithelial and mesenchymal markers in SK-OV-3 cells compared to their baseline mRNA expression in 59 M cells (n = 3). Values were normalised to beta 2 microglogublin (B2M). Data shown are mean value + SD. ****p ≤ 0.0001, ***p ≤ 0.001, **p ≤ 0.01, *p ≤ 0.05 was determined by Student’s t test