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Table 6 Effects of being treated according to the guidelines and time period on the probability of dying from all causes and cervical cancer by tumour stage (n = 1085)

From: Effect of changes in treatment practice on survival for cervical cancer: results from a population-based study in Manitoba, Canada

 

Any death

Death from cervical cancer

No. of death/Total

Adjusted HR (95 % CI)a

p-value

No. of death/Total

Adjusted HR (95 % CI)a

p-value

Stage IAb

      

 Treated according to guidelines

      

  No

1/54

1.00

0.08

0/54

-

 

  Yes

22/175

5.98 (0.80–44.83)

 

1/175

  

 Time period

      

  1984–1998

22/166

1.00

0.41

1/166

-

 

  1999–2008

1/63

0.42 (0.05–3.28)

 

0/63

  

Stage IB-IIA

      

 Treated according to guidelines

      

  No

29/97

1.00

0.84

19/97

1.00

0.43

  Yes

110/301

0.96 (0.63–1.47)

 

61/301

0.81 (0.48–1.38)

 

 Time period

      

  1984–1998

116/298

1.00

0.50

64/298

1.00

0.45

  1999–2008

23/100

0.85 (0.53–1.37)

 

16/100

0.80 (0.45–1.43)

 

Stage IIB-IVA

      

 Treated according to guidelines

      

  No

54/80

1.00

0.002

41/80

1.00

0.02

  Yes

207/326

0.60 (0.43–0.82)

 

144/326

0.64 (0.44–0.93)

 

 Time period

      

  1984–1998

178/237

1.00

0.004

115/237

1.00

0.04

  1999–2008

83/169

0.65 (0.48–0.87)

 

70/169

0.71 (0.51–0.98)

 

Stage IVB

      

 Treated according to guidelines

      

  No

2/2

1.00

0.63

2/2

1.00

0.55

  Yes

48/50

0.68 (0.14–3.30)

 

44/50

0.62 (0.13–3.02)

 

 Time period

      

  1984–1998

17/17

1.00

0.03

17/17

1.00

0.02

  1999–2008

33/35

0.43 (0.20–0.93)

 

29/35

0.38 (0.17–0.84)

 
  1. aHR was adjusted for age at diagnosis, histology, area of residence, time period and treatment according to the guidelines
  2. bThe HR for patients diagnosed with tumours stage IA patients was not calculated because there were no deaths from cervical cancer