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Table 6 Effects of being treated according to the guidelines and time period on the probability of dying from all causes and cervical cancer by tumour stage (n = 1085)

From: Effect of changes in treatment practice on survival for cervical cancer: results from a population-based study in Manitoba, Canada

  Any death Death from cervical cancer
No. of death/Total Adjusted HR (95 % CI)a p-value No. of death/Total Adjusted HR (95 % CI)a p-value
Stage IAb       
 Treated according to guidelines       
  No 1/54 1.00 0.08 0/54 -  
  Yes 22/175 5.98 (0.80–44.83)   1/175   
 Time period       
  1984–1998 22/166 1.00 0.41 1/166 -  
  1999–2008 1/63 0.42 (0.05–3.28)   0/63   
Stage IB-IIA       
 Treated according to guidelines       
  No 29/97 1.00 0.84 19/97 1.00 0.43
  Yes 110/301 0.96 (0.63–1.47)   61/301 0.81 (0.48–1.38)  
 Time period       
  1984–1998 116/298 1.00 0.50 64/298 1.00 0.45
  1999–2008 23/100 0.85 (0.53–1.37)   16/100 0.80 (0.45–1.43)  
Stage IIB-IVA       
 Treated according to guidelines       
  No 54/80 1.00 0.002 41/80 1.00 0.02
  Yes 207/326 0.60 (0.43–0.82)   144/326 0.64 (0.44–0.93)  
 Time period       
  1984–1998 178/237 1.00 0.004 115/237 1.00 0.04
  1999–2008 83/169 0.65 (0.48–0.87)   70/169 0.71 (0.51–0.98)  
Stage IVB       
 Treated according to guidelines       
  No 2/2 1.00 0.63 2/2 1.00 0.55
  Yes 48/50 0.68 (0.14–3.30)   44/50 0.62 (0.13–3.02)  
 Time period       
  1984–1998 17/17 1.00 0.03 17/17 1.00 0.02
  1999–2008 33/35 0.43 (0.20–0.93)   29/35 0.38 (0.17–0.84)  
  1. aHR was adjusted for age at diagnosis, histology, area of residence, time period and treatment according to the guidelines
  2. bThe HR for patients diagnosed with tumours stage IA patients was not calculated because there were no deaths from cervical cancer