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Fig. 5 | BMC Cancer

Fig. 5

From: Boronic prodrug of 4-hydroxytamoxifen is more efficacious than tamoxifen with enhanced bioavailability independent of CYP2D6 status

Fig. 5

Comparison of individual and total drug and metabolite concentrations in tumor tissues from mice treated with ZB497 or tamoxifen. Tamoxifen, 4-OHT, and desmethyltamoxifen (DMT) were detected and quantified in tumor tissues from tamoxifen treated mice. In tumor tissues from ZB497-treated mice, 4-OHT, endoxifen, B401 and B415 were detected and quantified

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BMC Cancer

ISSN: 1471-2407

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