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Fig. 7 | BMC Cancer

Fig. 7

From: Effects of cytochalasin congeners, microtubule-directed agents, and doxorubicin alone or in combination against human ovarian carcinoma cell lines in vitro

Fig. 7

Chou-Talalay method Fa-CI plots to assess drug synergy between cytochalasin B, 21,22-dihydrocytochalasin B, doxorubicin, and paclitaxel against SKOV3 and SKVLB1 human ovarian carcinomas. a Concomitant treatments against SKOV3 cells. b Concomitant treatments against SKVLB1 cells. Agents were administered continuously for 48 h. According to the Chou-Talalay method for the assessment of drug synergy [27], < 0.1 (very strong synergism), 0.1–0.3 (strong synergism), 0.3–0.7 (synergism), 0.7–0.85 (moderate synergism), 0.85–0.9 (slight synergism) are all values of synergism, while 0.9–1.1 may be considered additive or potentially antagonistic, and any values greater than 1.1 are antagonistic

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BMC Cancer

ISSN: 1471-2407

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