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Fig. 3 | BMC Cancer

Fig. 3

From: Neoadjuvant administration of Semliki Forest virus expressing interleukin-12 combined with attenuated Salmonella eradicates breast cancer metastasis and achieves long-term survival in immunocompetent mice

Fig. 3

Neoadjuvant effect of SFV-IL-12. a Schematic representation of the therapeutic protocol performed in this study. Two doses of SFV-LacZ, SFV-IL-12 or PBS were i.t. injected as in Fig. 2. Three days later (i.e. day 16 after 4T1 cells inoculation), treated tumors were surgically removed (S-16). b Kaplan–Meier plot shows the survival rate of treated and control mice (n = 5-10). Non-significant (n.s), p< 0.001 (***)

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