Fig. 3From: Neoadjuvant administration of Semliki Forest virus expressing interleukin-12 combined with attenuated Salmonella eradicates breast cancer metastasis and achieves long-term survival in immunocompetent miceNeoadjuvant effect of SFV-IL-12. a Schematic representation of the therapeutic protocol performed in this study. Two doses of SFV-LacZ, SFV-IL-12 or PBS were i.t. injected as in Fig. 2. Three days later (i.e. day 16 after 4T1 cells inoculation), treated tumors were surgically removed (S-16). b Kaplan–Meier plot shows the survival rate of treated and control mice (n = 5-10). Non-significant (n.s), p< 0.001 (***)Back to article page