Fig. 2
From: Texture analysis on MR images helps predicting non-response to NAC in breast cancer
Top, axial fat-suppressed T1 weighted imaging (time corresponding to the second post-contrast image). Two large ROIs, one encompassing the lesion (in red) and one encompassing normal breast tissues (in green), were defined for visual texture analysis. A small ROI (in yellow) in the brightest part of the lesion was also defined to study the kinetics of the contrast agent. Bottom, the signal intensity vs time curve (temporal sampling 60Â s) corresponding to the small ROI (from which kinetic parameters are derived) is displayed. Amplitude was calculated from the maximum enhancement peak, the wash-in parameter from the up-slope measurement (between the maximum enhancement peak and the preceding time point) and the wash-out parameter from linear regression performed on the last three time points of the signal intensity versus time curve