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Table 2 Association between SENP1 immunostaining results and prostate cancer phenotype in all cancers

From: The prognostic value of SUMO1/Sentrin specific peptidase 1 (SENP1) in prostate cancer is limited to ERG-fusion positive tumors lacking PTEN deletion

Parameter

SENP1

p value

n evaluable

Negative (%)

Weak (%)

Moderate (%)

Strong (%)

All cancers

9,516

65.5

12.3

14.9

7.3

 

Tumor stage

     

<0.0001

pT2

6,143

68.2

11.1

14.1

6.6

pT3a

2,137

61.8

13.7

15.9

8.7

pT3b-4

1,203

58.1

15.8

17.6

8.5

Gleason grade

     

<0.0001

≤3 + 3

2,135

72.5

9.2

11.6

6.7

3 + 4

5,451

65.3

11.7

15.5

7.5

4 + 3

1,445

58.4

16.2

17.6

7.8

≥4 + 4

442

58.1

20.8

14.9

6.1

Lymph node metastasis

     

0.0019

N0

5,472

62.3

12.6

16.6

8.5

N+

526

56.8

18.4

17.5

7.2

Preop. PSA level (ng/ml)

     

0.0037

<4

1160

64.2

12.2

15.9

7.6

4-10

5702

66.8

11.2

15.0

7.0

10-20

1892

63.4

14.6

14.5

7.5

>20

666

62.3

14.9

14.3

8.6

Surgical margin

     

0.3216

negative

7,549

65.9

12.1

14.9

7.1

positive

1,797

63.8

13.0

15.2

8.0