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Table 6 Univariate and multivariate Cox analysis of predictive factors for overall survival in 98 SOEC patients

From: Overexpression of Class III β-tubulin, Sox2, and nuclear Survivin is predictive of taxane resistance in patients with stage III ovarian epithelial cancer

Variables

Univariate

Multivariate

HR (95 % CI)

χ 2

P

HR (95 % CI)

χ 2

P

Age (years)

1.176 (0.530-2.611)

0.159

0.690

-

-

-

    <65

      

    ≥65

      

Histotype

1.390 (0.969-1.993)

3.198

0.074

2.015 (1.296-3.134)

9.680

0.002*

    Serous

      

    Others

      

Grade

   

-

-

-

    G1-2

1.318 (0.862-2.016)

1.627

0.202

   

    G3

      

Ascites (mL)

1.021 (0.576-1.811)

0.005

0.943

-

-

-

    <1000

      

    >1000

      

Residual tumor (cm)

3.814 (1.946-7.476)

15.204

<0.0001*

2.736 (1.271-5.890)

6.617

0.010*

    <1

      

    ≥1

      

Response to chemotherapy

5.627 (3.078-10.289)

31.483

<0.0001*

5.318 (2.677-10.564)

22.770

<0.0001*

    PR

      

    PD

      

Class III β-tubulin

1.347 (0.776-2.339)

1.119

0.290

-

-

-

    Positive

      

    Negative

      

Sox2

1.537 (0.863-2.736)

2.128

0.145

-

-

-

    Positive

      

    Negative

      

Nuclear Survivin

1.399 (0.813-2.407)

1.472

0.225

-

-

-

    Positive

      

    Negative

      

Cytoplasmic Survivin

1.206 (0.643-2.261)

0.341

0.559

-

-

-

    Positive

      

    Negative

      
  1. HR hazard ratios, CI confidence interval
  2. *P < 0.05; only variables with P < 0.10 in the univariate analysis were included in the multivariate model
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BMC Cancer

ISSN: 1471-2407

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