Variable | TWIST1 expression in breast tumor cellsa | TWIST1 expression in tumor stromaa | |||||
---|---|---|---|---|---|---|---|
N | Mean | SEM | p-valueb | Mean | SEM | p-valueb | |
All | 102 | 8.6 | 2.2 | NA | 40.6 | 4.2 | NA |
T-stage | |||||||
1 | 64 | 7.7 | 2.8 | 0.05 | 48.7 | 5.1 | 0.0007 |
>1 | 38 | 10.1 | 3.6 | 26.0 | 6.8 | ||
N-stage | |||||||
0 | 60 | 9.5 | 2.9 | 0.87 | 44.3 | 5.4 | 0.09 |
>1 | 42 | 7.3 | 3.4 | 35.0 | 6.6 | ||
Grade | |||||||
1 and 2 | 60 | 10.2 | 2.9 | 0.35 | 38.7 | 5.6 | 0.86 |
3 | 40 | 6.6 | 3.5 | 43.6 | 6.7 | ||
Histology | |||||||
IDC | 85 | 9.0 | 2.4 | 0.25 | 44.2 | 4.5 | 0.06 |
Other | 17 | 6.8 | 5.4 | 22.5 | 10.1 | ||
Hormone receptor status | |||||||
Negative | 16 | 1.8 | 5.9 | 0.23 | 36.8 | 11.0 | 0.53 |
Positive | 86 | 9.7 | 2.4 | 41.2 | 4.6 | ||
HER2 status | |||||||
Positive | 16 | 17.8 | 5.4 | 0.74 | 42.5 | 10.3 | 0.75 |
Negative | 86 | 6.8 | 2.4 | 40.2 | 4.6 | ||
Ki 67 (cut-off 14 %) | |||||||
Low | 51 | 9.1 | 3.1 | 0.83 | 39.0 | 5.9 | 0.60 |
High | 51 | 8.1 | 3.2 | 42.2 | 6.0 | ||
Epithelial CTC | |||||||
Present | 12 | 4.2 | 6.4 | 0.96 | 43.3 | 11.9 | 0.75 |
Absent | 90 | 9.2 | 2.4 | 40.2 | 4.5 | ||
EMT CTC | |||||||
Present | 16 | 7.8 | 5.5 | 0.62 | 42.2 | 10.3 | 0.98 |
Absent | 86 | 8.7 | 2.4 | 40.3 | 4.6 | ||
Any CTC | |||||||
Present | 25 | 6.2 | 4.4 | 0.71 | 44.6 | 8.2 | 0.68 |
Absent | 77 | 9.4 | 2.6 | 39.1 | 4.9 |