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Table 5 Pathway analysis of genetic changes in A2780 and A2780cis in response to hypoxia

From: Identifying novel hypoxia-associated markers of chemoresistance in ovarian cancer

Cell Line Pathway P-value Change in Expression
A2780 MAPK signalling 0.001 Up-Regulated
Focal adhesion 0.002
Renal Cell Carcinoma 0.01
Starch and Sucrose Metabolism 0.04
Complement and Coagulation Cascade 0.04
A2780cis MAPK signalling 0.02
Focal adhesion <0.001
Axon guidance 0.002
TGF beta signalling 0.007
Toll like receptor signalling 0.02
DNA replication <0.001
A2780 Cell cycle <0.001 Down-regulated
Pyrimidine metabolism <0.001
Base Excision Repair <0.001
Homologous Recombination <0.001
DNA replication <0.001
A2780cis Cell cycle <0.001
Pyrimidine metabolism 0.001
Base excision repair 0.004
Oxidative phosphorylation <0.001
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