Table 4 Significantly down-regulated pathways in A2780cis compared to A2780
From: Identifying novel hypoxia-associated markers of chemoresistance in ovarian cancer
Pathway | Genes | P-value |
|---|---|---|
Focal Adhesion | FYN, SHC4, ACTN3, CAV1, CAV2, COL1A2, COL6A3, FLNC, HGF, IGF1R, ITGA5, ITGA8, LAMA1, PIK3CA, PDGFD, PDGFA, SPP1, THBS1, AKT3, VAV3, VCL | <0.0001 |
Arrhythmogenic Right Ventricular Cardiomyopathy | CDH2, CACNG7, DSC2, DSG2, DMD, CACNA1C, JUP, SLC8a1, TCF7L1 | <0.0001 |
Melanoma | CDKN2A, FGF18, FGF20, FGF5 | 0.001 |
Axon Guidance | EPHA3, EPHA7, NTNG1, PLXNC1, ROBO2, SEMA3E, SEMA6A, SEMA6D, SLIT2, UNC5C | 0.006 |
Cell Adhesion Molecules | CDH2, CLDN17, CLDN8, CNTNAPA2, HLA-DPA1, HLA-DRB3, NEO1, NLGN4X, NEGR1, SDC2, VCAN | 0.006 |