Table 5 The correlations between the overall survival and various clinicopathological factors in the validation study

Age (>70 years)

4.070

1.718–9.646

0.001

0.469

0.095–2.313

0.353

Gender (Female)

1.335

0.578–3.085

0.499

Location of primary tumor (Rectum)

0.492

0.208–1.160

0.105

Tumor depth (T4)

1.524

0.668–3.480

0.317

0.625

0.163–2.391

0.492

Histological type (Poorly, Mucinous)

4.230

1.567–11.417

0.004

7.723

1.057–56.416

0.044

The number of lymph node metastases (≥4)

4.356

1.920–9.882

<0.001

5.707

1.279–25.465

0.022

Preoperative CEA (>5 ng/ml)

2.709

1.086–6.757

0.033

4.355

1.090–17.394

0.037

Preoperative CA19-9 (>37 U/ml)

1.740

0.401–7.538

0.459

Adjuvant chemotherapy (None)

0.399

0.093–1.707

0.215

1.110

0.198–6.230

0.906

The amount of blood lost (>100 ml)

0.794

0.335–1.882

0.600

0.271

0.070–1.050

0.059

Combination of pre and postoperative PNI (<43)

2.019

1.327–3.072

0.001

2.542

1.490–4.337

0.001