Fig. 1

a A glomerulus with FSGS. The red arrow marks the segmentally sclerosed region with obliteration of capillary tuft, hyaline deposition and adhesion to Bowman’s capsule. Jones methenamine silver, 40x objective. b A glomerulus with collapsing variant of FSGS. There is almost diffuse collapse of capillary loops with proliferation of overlying epithelial cells (yellow arrow). Jones methenamine silver, 40x objective. c An electron micrograph shows extensive effacement of foot processes (black arrows) over a capillary loop (cap) with corrugated glomerular basement membrane. 4800 X magnification