Group | Numbers | PFS (range) | P value | OS (range) | P value |
---|---|---|---|---|---|
MRD | Â | Â | 0.002 | Â | 0.001 |
   ≥ 1 % | 117 | 36 (26.8 ~ 45.1) |  | 72 (63.4 ~ 98.6) |  |
   < 1 % | 31 | Not reached |  | Not reached |  |
LDH | Â | Â | 0.001 | Â | <0.001 |
   ≥ 220U/L | 38 | 29 (19.2 ~ 38.8) |  | 37 (28.5 ~ 45.5) |  |
   < 220U/L | 83 | 52 (35.0 ~ 68.9) |  | 162 (70.7 ~ 253.3) |  |
CR | Â | Â | <0.001 | Â | <0.001 |
  Yes | 38 | 110 (27.2 ~ 192.8) |  | 63 (41 ~ 85) |  |
  No | 111 | 36.0 (29.0 ~ 43.0) |  | 25 (11 ~ 39) |  |
CR + PR |  |  | <0.001 |  | <0.001 |
  Yes | 88 | 63.0 (36.0 ~ 90.0) |  | 120.0 (93.2 ~ 146.8) |  |
  No | 61 | 25.0 (18.1 ~ 31.9) |  | 43.0 (28.8 ~ 57.2) |  |
β2-MG (mg/L) |  |  | 0.003 |  | 0.001 |
   ≥ 3.5 | 51 | 32 (22.7 ~ 41.3) |  | 57.0 (38.1 ~ 75.9) |  |
   < 3.5 | 42 | Not reached |  | Not reached |  |
Cytogenetic abnormalities | Â | Â | 0.005 | Â | 0.013 |
  High -risk | 37 | 28 (14.5 ~ 41.5) |  | 60 (49.2 ~ 70.8) |  |
  Non high-risk | 61 | 84 (17.8 ~ 150.2) |  | Not reached |  |