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Table 3 Surgical outcomes between radical surgery with extensive upper abdominal procedures and standard surgery

From: Radical surgery versus standard surgery for primary cytoreduction of bulky stage IIIC and IV ovarian cancer: an observational study

Variable Radical surgery group (n = 112) Standard surgery group (n = 241) P value*
Residual disease, in overall    <0.001
 0 cm 46 (41.1 %) 0 (0 %)  
 0.1–0.5 cm 46 (41.1 %) 27 (11.2 %)  
 0.5–1 cm 15 (13.4 %) 78 (32.4 %)  
 >1 cm 5 (4.5 %) 136 (56.4 %)  
Residual disease in upper abdomen   <0.001
 0 cm 76(67.9 %) 0(0 %)  
 0.1–0.5 cm 24(21.4 %) 30(12.4 %)  
 0.5–1 cm 10(8.9 %) 75(31.1 %)  
 >1 cm 2(1.8 %) 136(56.4 %)  
Estimated blood loss    <0.001
 Median volume 800 ml 600 ml  
 (range) (100–4000) (100–3000)  
Intraoperative blood transfusion    <0.001
 Median volume 800 ml 400 ml  
 (range) (0–3200) (0–2400)  
Operative time    <0.001
Median 171 min 124 min  
(range) (75–360) (51–318)  
ICU stay    0.018
 Yes 28 (25.0 %) 35 (14.5 %)  
 No 84 (75.0 %) 206 (85.5 %)  
Length of hospitalization    <0.001
Mean 19.96 days 10.39 days  
(range) (4–190)b (4–42)  
  1. *Tested by Chi-square or Mann–Whitney U.b33 patients (29.5 %) in radical surgery group participated in a phase II clinical trial on intraperitoneal chemotherapy and were assigned to receive IP chemotherapy for 4 cycles weekly post operative in hospital, whereas only 7 patients (1.7 %) in standard surgery group participated in this trial and received IP chemotherapy. One patient stayed in hospital for 190 days because she received all the cycles of IP and IV chemotherapy in hospital