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Table 3 Surgical outcomes between radical surgery with extensive upper abdominal procedures and standard surgery

From: Radical surgery versus standard surgery for primary cytoreduction of bulky stage IIIC and IV ovarian cancer: an observational study

Variable

Radical surgery group (n = 112)

Standard surgery group (n = 241)

P value*

Residual disease, in overall

  

<0.001

 0 cm

46 (41.1 %)

0 (0 %)

 

 0.1–0.5 cm

46 (41.1 %)

27 (11.2 %)

 

 0.5–1 cm

15 (13.4 %)

78 (32.4 %)

 

 >1 cm

5 (4.5 %)

136 (56.4 %)

 

Residual disease in upper abdomen

 

<0.001

 0 cm

76(67.9 %)

0(0 %)

 

 0.1–0.5 cm

24(21.4 %)

30(12.4 %)

 

 0.5–1 cm

10(8.9 %)

75(31.1 %)

 

 >1 cm

2(1.8 %)

136(56.4 %)

 

Estimated blood loss

  

<0.001

 Median volume

800 ml

600 ml

 

 (range)

(100–4000)

(100–3000)

 

Intraoperative blood transfusion

  

<0.001

 Median volume

800 ml

400 ml

 

 (range)

(0–3200)

(0–2400)

 

Operative time

  

<0.001

Median

171 min

124 min

 

(range)

(75–360)

(51–318)

 

ICU stay

  

0.018

 Yes

28 (25.0 %)

35 (14.5 %)

 

 No

84 (75.0 %)

206 (85.5 %)

 

Length of hospitalization

  

<0.001

Mean

19.96 days

10.39 days

 

(range)

(4–190)b

(4–42)

 
  1. *Tested by Chi-square or Mann–Whitney U.b33 patients (29.5 %) in radical surgery group participated in a phase II clinical trial on intraperitoneal chemotherapy and were assigned to receive IP chemotherapy for 4 cycles weekly post operative in hospital, whereas only 7 patients (1.7 %) in standard surgery group participated in this trial and received IP chemotherapy. One patient stayed in hospital for 190 days because she received all the cycles of IP and IV chemotherapy in hospital