Table 2 Uni- and multivariate analyses

Univariate analysis (log-rank)

p-value

ᅟGender (male vs. female)

0.587

ᅟAge (>/< median)

0.498

ᅟExtracerebral tumor control (yes vs. no)

<0.001

ᅟKPS (grouped 90–100 vs. 70–80 vs. <70)

0.649

ᅟRPA (1 vs. 2 vs. 3)

0.027

ᅟds-GPA (2 vs. 3 vs. 4)

0.011

ᅟWBRT (yes vs. no)

0.082

ᅟSymptoms prior to SRS (yes vs. no)

0,228

ᅟNumber of BM (grouped 1 vs. 2–3 vs. >3)

0.005

ᅟNumber of BM (total)

0.007

ᅟLocation (infra- vs. supratentorial)

0.792

ᅟResponse to SRS (remission vs. stable vs. progression)

<0.001

ᅟSize of BM (>/< median)

0.125

Multivariate Analysis (Cox-regression model)

p-value

ᅟExtracerebral tumor control (yes vs. no)

<0.001

ᅟds-GPA (2 vs. 3 vs. 4)

0.078

ᅟRPA (1 vs. 2 vs. 3)

0.208

ᅟNumber of BM (grouped 1 vs. 2–3 vs. >3)

0.006

ᅟResponse to SRS

<0.001