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Table 2 The methylation proportion of miR-9 genes in different EOC cell lines

From: Methylation-associated Has-miR-9 deregulation in paclitaxel- resistant epithelial ovarian carcinoma

  SKOV3 SK-treated ST30 A2780 A2780-treated A2780R
miR-9-1 48.89 % 64.44 %# 65.56 %* 78.33 % 92.22 %# 93.33 %*
miR-9-2 74.07 % 78.70 % 75.76 % 4.44 % 11.11 % 10.10 %
miR-9-3 21.56 % 28.29 %## 55.84 %** 11.43 % 18.86 %## 88.05 %**
  1. The methylation proportions of miR-9-1 and miR-9-3 in ST30 and A2780 cells were significantly higher compared with their parent paclitaxel sensitive EOC cell lines SKOV3 and A2780, *P = 0.001 and 0.000, **P = 0.000 and 0.000. The methylation proportions of miR-9-1 and miR-9-3 were also increased significantly in paclitaxel treated SKOV3 and A2780 cells. #P = 0.002 and 0.000, ##P = 0.035 and 0.005