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Table 2 Distribution frequency of normal/CIN1, CIN2, and CIN3 + lesions by method of biopsy, grouped by cervical quadrant location

From: Distribution of cervical intraepithelial neoplasia on the cervix in Chinese women: pooled analysis of 19 population based screening studies

Quadrants Diagnosis
   Normal/CIN1 CIN2 CIN3+ Total
   n n/Nr(%) 95%CI n n/Nr(%) 95%CI n n/Nr(%) 95%CI Nr Nr/N(%)
Directed biopsy             
  Q1 1968 88.1 86.7 89.4 129 5.8 4.9 6.8 136 6.1 5.2 7.1 2233 4.2
  Q2 1583 83.2 81.5 84.8 167 8.8 7.6 10.1 153 8.0 6.9 9.3 1903 3.6
  Q3 1548 82.8 81.1 84.5 146 7.8 6.7 9.1 175 9.4 8.1 10.8 1869 3.5
  Q4 2238 88.4 87.1 90.0 126 5.0 4.2 5.9 169 6.7 5.7 7.7 2533 4.8
P < 0.0001              
Random biopsy             
  Q1 8698 98.2 97.9 98.5 87 1.0 0.8 1.2 72 0.8 0.6 1.0 8857 16.7
  Q2 8873 97.9 97.6 98.2 106 1.2 1.0 1.4 80 0.9 0.7 1.1 9059 17.1
  Q3 8717 97.8 97.5 98.1 118 1.3 1.1 1.6 77 0.9 0.7 1.1 8912 16.8
  Q4 8521 98.2 97.9 98.4 94 1.1 0.9 1.3 65 0.7 0.6 0.9 8680 16.4
P = 0.1911              
ECC               
   8766 96.9 96.6 97.3 101 1.1 0.9 1.4 175 1.9 1.7 2.2 9042 17.0
Total   50912 95.9 95.7 96.1 1074 2.0 1.9 2.1 1102 2.1 2.0 2.2 53088 100.0
  1. CIN cervical intraepithelial neoplasia; Q quadrant; ECC endocervical curettage; CI confidence interval