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Table 1 Overlap between selected top features from CCLE and CGP. For each drug, the table shows the number of common genes between CCLE_Impor and CGP_Impor and overlapping significance by Fisher’s exact test

From: Anticancer drug sensitivity prediction in cell lines from baseline gene expression through recursive feature selection

Drug

1-500

p-value

501-1000

p-value

1001-1500

p-value

AZD6244

79

3.716

49

3.277

30

3.48

e-25

 

e-8

 

e-2

Erlotinib

79

3.716

47

2.225

38

3.47

e-25

 

e-7

 

e-4

PHA665752

72

1.603

40

8.163

33

7.76

e-20

 

e-5

 

e-3

AZD0530

72

1.603

42

1.722

32

1.32

e-20

 

e-5

 

e-2

Paclitaxel

74

8.309

45

1.368

39

1.71

e-22

 

e-6

 

e-4

PF-2341066

80

7.541

41

3.801

28

8.06

e-26

 

e-5

 

e-2

Sorafenib

79

3.716

31

2.177

22

0.46

e-25

 

e-2

  

PD-0325901

78

1.80

54

1.803

28

8.06

e-24

 

e-10

 

e-2

Lapatinib

68

4.78

46

5.586

33

7.76

e-18

 

e-7

 

e-3

PLX4720

78

1.80

41

3.801

29

5.38

e-24

 

e-5

 

e-2

PD-0332991

68

4.78

39

1.706

28

8.06

e-18

 

e-4

 

e-2