Fig. 4

Box plot diagram showing mean cell survival in the breast cancer spheroid model after cytostatic treatment in comparison to the remaining tumor as determined by the pathological assessment of the surgical specimen after chemotherapy. Proposed cutoff of 35 % is represented by the dotted line. ypT0/ypN0 = 24.4 % (n = 19), ypTis =5.1 % (n = 4; ypN0 2 out of 3), ypT1 = 33.3 % (n = 26), ypT2 = 20.5 % (n = 16), ypT3 = 10.3 % (n = 8), ypT4 = 1.3 % (n = 1), not documented (n = 4), * represents an outlier