Skip to main content

Table 3 Univariate analysis of patients’ 5-year overall survival

From: c-Met in esophageal squamous cell carcinoma: an independent prognostic factor and potential therapeutic target

Variable P-value Hazard ratio (95 % CI)
Age (≥64/<64 years) (mean, 64 years) 0.992 1.003 (0.557–1.809)
Sex (male/female) 0.036a 2.621 (1.057–8.724)
Tumor size (≥48.7/<48.7 mm) (mean, 48.7 mm) 0.099 1.639 (0.912–2.971)
Tumor differentiation (well/moderate) 0.302 0.682 (0.303–1.390)
(well/poor) 0.143 0.484 (0.185–1.290)
(moderate/poor) 0.41 0.710 (0.340–1.671)
Growth pattern (INFa/INFb) 0.725 0.878 (0.402–1.774)
(INFa/INFc) 0.158 0.528 (0.216–1.290)
(INFb/INFc) 0.193 0.602 (0.297–1.316)
Lymphatic invasion (ly1–3/ly0) 0.015* 2.392 (1.174–5.536)
Venous invasion (v1–3/v0) 0.763 1.109 (0.581–2.295)
Tumor depth (pT3–4/pT1–2) 0.015a 2.265 (1.164–4.835)
Lymph node metastasis (pN1/pN0) <0.001a 4.692 (2.139–12.358)
Distant metastasis (pM1/pM0) 0.086 2.308 (0.875–5.069)
Pathological stage (pStage III–IV/I–II) <0.001a 3.403 (1.840–6.620)
c-Met expression (high/low) 0.017a 2.291 (1.153–5.073)
HGF expression (high/low) 0.194 1.477 (0.817–2.662)
  1. CI confidence interval, HGF hepatocyte growth factor, INF infiltration
  2. a indicates statistical significance