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Table 1 Main characteristics of the eligible studies

From: Lymph node density as a prognostic variable in node-positive bladder cancer: a meta-analysis

Study Year Country Recruitment period Prospective data collection Inclusion and exclusion criteria Definition of survival Definition of LN density Cut-off of LN density Interpretation of LN density Quality scale
Herr [5] 2003 USA 1979–1999 No No No Yes 20 NA 3
Fleischmann [18] 2005 Switzerland 1985–2000 Yes Yes Yes No 20 NA 5
Osawa [19] 2009 Japan 1990–2005 No Yes No No 25 NA 4
Wiesner [20] 2009 Germany 2001–2006 Yes No No No 11 NA 3
Furukawa [21] 2010 Japan 1995–2003 No Yes No No 25 NA 4
Guzzo [22] 2010 USA 1988–2003 Yes Yes No Yes 25 NA 5
Stephenson [23] 2010 USA 1999–2007 No No No No 20 Blind 3
May [24] 2011 Germany 1989–2008 No Yes No Yes 20 NA 5
Jensen [25] 2012 Denmark 2004–2009 Yes Yes Yes Yes 10 NA 6
Morgan [26] 2012 USA 1992–2006 No Yes Yes Yes 20 NA 4
Kassouf [27] 2013 Multination 1993–2005 No Yes Yes No None* NA 4
Masson-Lecomte [28] 2013 France 2002–2011 No No No Yes 20 NA 4
Mmeje [29] 2013 USA 2005–2009 No No Yes Yes 20 NA 4
Kwon [30] 2014 Korea 1990–2011 No Yes Yes No 18 NA 4
  1. LND: lymph node density, NA: not available