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Table 1 Patients’ baseline characteristics

From: Pegylated liposomal doxorubicin (Lipo-Dox®) combined with cyclophosphamide and 5-fluorouracil is effective and safe as salvage chemotherapy in taxane-treated metastatic breast cancer: an open-label, multi-center, non-comparative phase II study

 

Number (%)

Median Age, years

52.5

ECOG performance status

 

0

4 (8.9)

1

36 (80.0)

2

5 (11.1)

Initial stage at diagnosis

 

I

6 (14.6)

II

20 (38.8)

III

6 (14.7)

IV

9 (22.0)

Metastatic site

 

Locally advanced

4 (8.9)

Regional lymph nodes

7 (15.6)

Distant lymph nodes

14 (31.1)

Lung

18 (40.0)

Liver

17 (37.8)

Bone

25 (55.6)

Skin/Soft tissue

8 (17.8)

Others

13 (28.9)

Number of metastatic sites

 

0-1

9 (20.00)

2

11 (24.44)

≥3

25 (55.56)

Previous anthracycline

 

Yes

7 (16.28)

No

36 (83.72)

Estrogen receptor

 

Positive

26 (57.78)

Negative

16 (35.56)

Unknown

3 (6.67)

Her-2 expressiona

 

0, 1+

30 (66.67)

2+

4 (8.89)

3+

5 (11.11)

Unknown

6 (13.33)

  1. Abbreviations: ECOG, Eastern Cooperative Oncology Group
  2. aHer-2 expression was determined by immunohistochemical staining