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Table 1 Demographic characteristics of all mothers, mothers of cases and mothers of controls, and birth outcomes for all offspring, for cases and controls
| Cases (%) | Controls (%) | Total | |
|---|---|---|---|
| Maternal country of birth | |||
| Europe, USA, Canada | 14.102 (95.3) | 139.949 (94.7) | 154,051 |
| Middle-East* | 262 (1.8) | 2.732 (1.8) | 2.994 |
| Africa excluding North-Africa | 77 (0.5) | 823 (0.6) | 900 |
| Asia** | 155 (1.0) | 1.897 (1.3) | 2.052 |
| Central and South-America | 105 (0.7) | 1.085 (0.7) | 1.190 |
| Other countries and missing | 104 (0.7) | 1.223 (0.8) | 1.327 |
| Maternal age, in years | |||
| <20 | 601 (4.1) | 6.227 (4.2) | 6.828 |
| 20–24 | 3.423 (23.1) | 35.446 (24.0) | 38.869 |
| 25–29 | 5.385 (36.4) | 53.690 (36.3) | 59.075 |
| 30–34 | 3.716 (25.1) | 36.561 (24.8) | 40.277 |
| >34 | 1.680 (11.3) | 15.785 (10.7) | 17.465 |
| Smoking*** | |||
| Nonsmoker | 2.042 (13.8) | 21.011 (14.2) | 23.053 |
| Smoker | 1.264 (8.5) | 12.418 (8.4) | 13.682 |
| Missing | 11.499 (77.7) | 114.280 (77.4) | 125.779 |
| Hyperemesis status | |||
| HG + | 97 (0.7) | 818 (0.6) | 915 |
| HG - | 14.708 (99.3) | 146.891 (99.4) | 161.599 |
| Birth weight (gr) | |||
| <1500 | 97 (0.7) | 1.021 (0.7) | 1.118 |
| 1500–2499 | 549 (3.7) | 5.602 (3.8) | 6.151 |
| 2500–3499 | 6.046 (40.8) | 63.972 (43.3) | 70.018 |
| >3500 | 8.067 (54.5) | 76.771 (52.0) | 84.838 |
| Missing | 46 (0.3) | 343 (0.2) | 389 |
| Placental weight (gr)**** | |||
| <500 | 411 (2.8) | 4.177 (2.8) | 4.588 |
| 500–999 | 2.492 (16.8) | 24.872 (16.8) | 27.364 |
| ≥1000 | 112 (0.8) | 929 (0.8) | 1.041 |
| Missing | 11.790 (79.6) | 117.731 (79.7) | 129.521 |
| Apgar score after 1 min***** | |||
| < 7 | 659 (4.5) | 5.597 (3.8) | 6.256 |
| ≥ 7 | 11.760 (79.4) | 117.986 (79.9) | 129.746 |
| Missing | 2.386 (16.1) | 24.126 (16.3) | 26.512 |
| Apgar score after 5 min***** | |||
| < 7 | 161 (1.1) | 1.400 (0.9) | 1.561 |
| ≥ 7 | 12.558 (84.8) | 125.480 (85.0) | 138.038 |
| Missing | 2.086 (14.1) | 20.829 (14.1) | 22.915 |
| Total | 14.805 | 147.709 | 162.514 |
