Fig. 3

Mutation frequencies and immunohistochemistry scores for 37 mucinous carcinoma. As in Fig. 2, Solid color in any of the first 13 columns represents a presumed somatic (COSMIC) hotspot mutation in the given case. In the last three columns numbers represent binarized IHC score for p53 and ^§ “Original ERBB2 amplification and KRAS mutation” status derived from Anglesio et al., 2013 [13] where 0 = Negative, 1 = Positive, X = Unknown, the latter derived from IHC, FISH, and/or CISH. IHC for p53 is displayed as three-tiered IHC score where 0 (no staining) and 2 (>50 % positive nuclei) represent abnormal p53 status and 1 (1-50 % positive nuclei) represents normal p53 status