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Table 2 List of 28 genes involved in breast cancer a

From: Gene expression profiling leads to discovery of correlation of matrix metalloproteinase 11 and heparanase 2 in breast cancer progression

 

Gene

Fold change

 

Symbol

Description

Luminal A

Luminal B

Triple negative

1

GRIA4

Glutamate receptor, ionotropic, AMPA 4

−36.73

−10.59

−22.19

2

PIGR

Polymeric immunoglobulin receptor

−89.25

−24.54

−55.02

3

TUBB3

Tubulin, beta 3 class III

11.60

13.94

22.60

4

SLC26A3

Solute carrier family 26 (anion exchanger), member 3

−11.33

−10.86

−16.08

5

LINC00844

Long intergenic non-protein coding RNA 844

−15.33

−25.99

−13.74

6

FIGF

c-Fos induced growth factor

−49.22

−37.19

−18.18

7

SMYD1

SET and MYND domain containing 1

−31.85

−12.84

−17.43

8

CXCL2

Chemokine (C-X-C motif) ligand 2

−30.24

−13.34

−16.54

9

ALB

Albumin

−76.81

−54.76

−109.05

10

DRD2

Dopamine receptor D2

−19.79

−15.78

−10.30

11

DLK1

Delta-like 1 homolog

−82.62

−47.07

−19.17

12

RNF186

Ring finger protein 186

−64.51

−23.30

−61.59

13

C2orf40

Chromosome 2 open reading frame 40

−69.81

−13.55

−18.39

14

OXTR

Oxytocin receptor

−48.00

−24.36

−28.75

15

DAPL1

Death associated protein-like 1

−20.83

−20.53

−25.10

16

COL10A1

Collagen, type X, alpha 1

36.84

13.82

39.31

17

FGFBP1

Fibroblast growth factor binding protein 1

−50.79

−50.39

−17.39

18

NTRK2

Neurotrophic tyrosine kinase, receptor, type 2

−23.96

−15.75

−48.94

19

SCARA5

Scavenger receptor class A, member 5

−21.61

−19.18

−39.67

20

DLK2

Delta-like 2 homolog

−28.32

−11.49

−15.35

21

AFP

Alpha-fetoprotein

−29.03

−14.92

−42.89

22

HPSE2

Heparanase 2

−29.29

−20.28

−15.26

23

CAPN6

Calpain 6

−28.50

−38.50

−13.62

24

LINC00640

Long intergenic non-protein coding RNA 640

−18.13

−22.01

−12.84

25

LRRC3B

Leucine rich repeat containing 3B

−13.77

−21.02

−13.11

26

IL22RA2

Interleukin 22 receptor, alpha 2

−12.01

−22.72

−14.56

27

KCNJ16

Potassium inwardly-rectifying channel, subfamily J, member 16

−35.51

−11.58

−17.09

28

MMP11

Matrix metallopeptidase 11

24.75

12.45

50.25

  1. aGenes with corrected p-value < 0.05 and fold changes ≥ 10 in all the 3 subtypes using GeneSpring 12.6 software