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Table 2 List of 28 genes involved in breast cancer a

From: Gene expression profiling leads to discovery of correlation of matrix metalloproteinase 11 and heparanase 2 in breast cancer progression

  Gene Fold change
  Symbol Description Luminal A Luminal B Triple negative
1 GRIA4 Glutamate receptor, ionotropic, AMPA 4 −36.73 −10.59 −22.19
2 PIGR Polymeric immunoglobulin receptor −89.25 −24.54 −55.02
3 TUBB3 Tubulin, beta 3 class III 11.60 13.94 22.60
4 SLC26A3 Solute carrier family 26 (anion exchanger), member 3 −11.33 −10.86 −16.08
5 LINC00844 Long intergenic non-protein coding RNA 844 −15.33 −25.99 −13.74
6 FIGF c-Fos induced growth factor −49.22 −37.19 −18.18
7 SMYD1 SET and MYND domain containing 1 −31.85 −12.84 −17.43
8 CXCL2 Chemokine (C-X-C motif) ligand 2 −30.24 −13.34 −16.54
9 ALB Albumin −76.81 −54.76 −109.05
10 DRD2 Dopamine receptor D2 −19.79 −15.78 −10.30
11 DLK1 Delta-like 1 homolog −82.62 −47.07 −19.17
12 RNF186 Ring finger protein 186 −64.51 −23.30 −61.59
13 C2orf40 Chromosome 2 open reading frame 40 −69.81 −13.55 −18.39
14 OXTR Oxytocin receptor −48.00 −24.36 −28.75
15 DAPL1 Death associated protein-like 1 −20.83 −20.53 −25.10
16 COL10A1 Collagen, type X, alpha 1 36.84 13.82 39.31
17 FGFBP1 Fibroblast growth factor binding protein 1 −50.79 −50.39 −17.39
18 NTRK2 Neurotrophic tyrosine kinase, receptor, type 2 −23.96 −15.75 −48.94
19 SCARA5 Scavenger receptor class A, member 5 −21.61 −19.18 −39.67
20 DLK2 Delta-like 2 homolog −28.32 −11.49 −15.35
21 AFP Alpha-fetoprotein −29.03 −14.92 −42.89
22 HPSE2 Heparanase 2 −29.29 −20.28 −15.26
23 CAPN6 Calpain 6 −28.50 −38.50 −13.62
24 LINC00640 Long intergenic non-protein coding RNA 640 −18.13 −22.01 −12.84
25 LRRC3B Leucine rich repeat containing 3B −13.77 −21.02 −13.11
26 IL22RA2 Interleukin 22 receptor, alpha 2 −12.01 −22.72 −14.56
27 KCNJ16 Potassium inwardly-rectifying channel, subfamily J, member 16 −35.51 −11.58 −17.09
28 MMP11 Matrix metallopeptidase 11 24.75 12.45 50.25
  1. aGenes with corrected p-value < 0.05 and fold changes ≥ 10 in all the 3 subtypes using GeneSpring 12.6 software