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Fig. 1 | BMC Cancer

Fig. 1

From: Dysregulated cholinergic network as a novel biomarker of poor prognostic in patients with head and neck squamous cell carcinoma

Fig. 1

Kaplan-Meier estimated overall (OS) and disease-free survival (DFS) rates according to ChE activity values. Tumours (n = 57) were split into those that exhibited higher or lower values than the 50th percentile for AChE activity (1.801 mU/mg protein; a, c), for BChE activity (2.967 mU/mg tissue; b, d) or for the combination of AChE and BChE for OS (e) and DFS (f). Low tumour AChE activity was found to be statistically associated with adverse OS rate (p = 0.014) (a), but not with shorter DFS rate (p = 0.560) (c). High BChE activity in tumours was associated with both adverse OS (p = 0.020, b) and DFS (p = 0.030; d). The combination of AChE and BChE (“AChE high/BChE low” vs “AChE low/BChE high”) were statistically linked with adverse OS (p = 0.002) (e) and DFS (p = 0.047) (f)

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