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Fig. 7 | BMC Cancer

Fig. 7

From: The role of c-Src in the invasion and metastasis of hepatocellular carcinoma cells induced by association of cell surface GRP78 with activated α2M

Fig. 7

Association of Cell surface GRP78 with α2M* facilitated the maximal activation of EGFR in a c-Src dependent manner. (a) Western blot analysis of the expression and phosphorylation of EGFR in serum starved QGY-7703 treated with vehicle, α2M*, PP2 or PP2 in combination with α2M*. (b) Quantitative analysis of the expression and phosphorylation of EGFR in serum starved QGY-7703 treated with vehicle, α2M*, PP2 or PP2 in combination with α2M*. (c) Co-immunoprecipitation analysis of the interaction between c-Src and EGFR in serum starved QGY-7703 cells treated with vehicle, α2M*, PP2 or PP2 in combination with α2M*. (d) Quantitative analysis of the interaction between c-Src and EGFR in serum starved QGY-7703 cells treated with vehicle, α2M*, PP2 or PP2 in combination with α2M*

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BMC Cancer

ISSN: 1471-2407

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