Table 3 Predictive factors for disease-free survival of UTUC patients after RNU

Age (y)

≥70 vs <70

0.996 (0.969-1.023)

0.761

Sex

Male vs female

2.079 (1.268-3.409)

0.004

2.171 (1.340-3.516)

0.002

BMI (kg/m2)

≥25 vs <25

1.078 (0.648-1.791)

0.773

Tumor side

Left vs Right

1.293 (0.782-2.137)

0.316

Tumor location

Ureter vs Pelvis

2.243 (1.171-4.296)

0.015

1.526 (0.951-2.448)

0.080

Tumor multiplicity

Multiple vs Single

1.954 (1.180-3.234)

0.009

1.820 (1.132-2.925)

0.013

Tumor size (cm)

≥3.5 vs <3.5

1.293 (0.782-2.137)

0.316

Tumor configuration

Nonpapillary vs Papillary

0.722 (0.369-1.414)

0.343

T stage

T2-T4 vs Ta-T1

2.041 (1.173-4.195)

0.012

1.836 (1.132-3.125)

0.022

G grade

High vs Low

0.831 (0.471-1.467)

0.523

eGFR (ml/min/1.73 m²)

<60 vs ≥60

0.822 (0.483-1.400)

0.471

Hydronephrosis

Present vs Absent

0.552 (0.288-1.057)

0.073

Lymph node stage

N+ vs N0

1.437 (0.458-4.512)

0.535

KPNA2 expression

High vs Low

3.424 (1.972-5.944)

0.000

2.754 (1.683-4.506)

0.001