Figure 6From: Significance of KRAS/PAK1/Crk pathway in non-small cell lung cancer oncogenesisKRAS inhibition dephosphorylates Crk-II on serine 41. Western blots demonstrating loss of Crk-II phosphorylation on serine 41 in Rh2 NSCLC cells following 24 hour exposure of cells to combination of (F) farnesyltransferase inhibitor (BMS-225975 at 2 μM) and (G) geranylgeranyltransferase inhibitor (P61A6 at 2 μM).Back to article page