Figure 3
From: Significance of KRAS/PAK1/Crk pathway in non-small cell lung cancer oncogenesis
PAK1 activation is inversely correlated with E-cadherin and p120-catenin expression in NSCLC cells. A-Western blots demonstrating E-cadherin, p120-catenin, PAK1 and p-PAK1(Thr423) expression in a panel of NSCLC cells as well as immortalized normal human respiratory epithelial cells (BEAS-2B). B-Bar chart demonstrating signal intensity of p-PAK1/PAK1, p120-catenin and E-cadherin normalized to the value of BEAS-2B cells.